New Data on Posiphen in Traumatic Brain Injury

QR Pharma, Inc. Presents New Data on Posiphen in Traumatic Brain Injury at

2016 Military Health System Research Symposium

–Posiphen Reverses Behavioral Deficits and Neuropathology Caused by Traumatic Brain Injury–

Berwyn, Pa., August 17, 2016 — QR Pharma, Inc., a privately held Phase 2 biopharmaceutical company

developing novel therapies for the treatment of Alzheimer’s, Parkinson’s and other neurodegenerative

diseases, today announced the presentation of non-clinical data relating to its lead clinical product candidate,

Posiphen, at the 2016 Military Health System Research Symposium (MHSRS) being held August 15 – 18 in

Orlando, Florida.

The presentation highlighted studies conducted by investigators from The David Geffen School of Medicine at

UCLA characterizing the effects of Posiphen in a non-clinical model of traumatic brain injury (TBI). These

blinded studies revealed that Posiphen (2.5, 5 and 10 mg/kg) administered daily attenuated spatial working

memory deficits while also rescuing tissue damage, normalizing inflammation and reversing the molecular

pathology caused by TBI.

“These are impressive results for Posiphen in a high-fidelity rodent model of TBI,” commented Marie-Françoise

Chesselet, M.D., Ph.D., Professor and Interim Chair of the Department of Neurology at UCLA and principle

investigator for the studies. “Posiphen completely rescues working memory and consistently improves cell

function and survival in the substantia nigra and striatum, regions of the brain that are often damaged following

repeated TBI leading to the onset of Parkinson’s disease.”

“These studies provide further confirmation of the neuroprotective effects of Posiphen,” stated Maria

Maccecchini, Ph.D., President and CEO of QR Pharma. “These results add to a deep data set supporting the

unique activity and potentially broad application of Posiphen in TBI and other neurodegenerative conditions,

such as Parkinson’s and Alzheimer’s.”

A full copy of the MHSRS poster entitled, “Posiphen reverses behavioral deficits and neuropathology in a rat

model of mild traumatic brain injury,” can be accessed by visiting the “Scientific Presentations” in the Press

Room section of QR Pharma’s website at

About QR Pharma, Inc.

Headquartered in Berwyn, Pennsylvania, QR Pharma, Inc. is a clinical-stage specialty pharmaceutical

company committed to developing therapeutics with novel approaches for the treatment of cognitive

impairment in neurological disorders.

QR is currently developing Posiphen as a disease-modifying drug for acute as well as chronic

neurodegeneration and BNC for advanced Alzheimer’s disease. For more information on QR Pharma, please

visit the company’s website,

Contact: Maria Maccecchini

Tel: 610-727 3710

Fax: 610 727 4001


Posiphen poster MHSRS